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Third Epizyme-discovered product candidate advances into clinical development
September 15, 2016
By: Tim Wright
Editor-in-Chief, Contract Pharma
Epizyme, a clinical-stage biopharmaceutical company creating novel epigenetic therapeutics, has earned a $6 million milestone payment from GlaxoSmithKline (GSK). The milestone payment follows GSK’s initiation of patient dosing in a Phase 1 clinical trial of GSK3326595 (formerly EPZ015938), a first-in-class protein arginine methyltransferase-5 (PRMT5) inhibitor discovered by Epizyme and licensed to GSK. PRMT5 is a protein methyltransferase that is associated with a number of human cancers. “Ep...
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